| 货号 | 4371/50 |
| 别名 | N-[3-Chloro-4-[[(2-chlorophenyl)ami |
| 供应商 | Tocris |
| 生物活性 | Positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 422.29 |
| 分子式 | C18H13Cl2N3< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Robichaudet al (2011) Recent progress on the identification of metabotropic glutamate 4 receptor ligands and their potential utility as CNS therapeutics. ACS Chem.Neurosci. 2433. Engerset al (2010) Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS). Bioorg.Med.Chem.Lett. 20 5175. PMID: 20667732. |