| 货号 | 1966/50 |
| 别名 | (5Z,8Z,11Z,14Z)-N-(3-Furanylmethyl) |
| 供应商 | Tocris |
| 生物活性 | Potent endocannabinoid transport inhibitor. IC50 values are 0.8 and 30 μM for inhibition of the anandamide transporter and FAAH respectively. Ki values are 4700, 67 and > 5000 nM for CB1, CB2and VR1 receptors respectively. Potentiates hypokinetic and antinociceptive effects of anandamide in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 383.57 |
| 分子式 | C25H37NO2 |
| 可溶性/溶解性 | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
| CAS号 | 390824-20-1 |
| 参考文献 | Lopez-Rodriguezet al (2003) Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors. Eur.J.Med.Chem. 38 403. PMID: 12750028. Lopez-Rodriguezet al (2003) Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: comparison with effects on fatty acid amidohydrolase. J.Med.Chem. 46 1512. PMID: 12672252. |