TCN 238 (50 MG)
货号：
4259/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 4259/50 |
| 别名 | (E)-4-(2-Phenylethenyl)-2-pyrimidinamine |
性能| 供应商 | Tocris |
| 生物活性 | Positive allosteric modulator of mGlu4 receptors (EC50 = 1.0 μM for human and rat mGlu4 receptors). Orally available and brain penetrant. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 197.24 |
| 分子式 | C12H11N3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| 参考文献 | Eastet al (2010) An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction. Bioorg.Med.Chem.Lett. 20 4901. PMID: 20638279. |
