SC 79 (50 MG)
货号：
4635/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 4635/50 |
| 别名 | 2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester |
性能| 供应商 | Tocris |
| 生物活性 | Activator of Akt; binds to the pleckstrin homology domain of Akt. Enhances Akt phosphorylation by upstream protein kinases; also enables cytosolic activation of Akt. Shown to suppress excitotoxicity-induced neuronal death in vitroandin vivo. Exhibits brain penetrance. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 364.78 |
| 分子式 | C17H17ClN2O5 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Joet al (2012) Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death. Proc.Natl.Acad.Sci.USA 109 10581. PMID: 22689977. |
