SANT-1 (50 MG)
货号：
1974/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 1974/50 |
| 别名 | N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine |
性能| 供应商 | Tocris |
| 生物活性 | Potent, cell-permeable inhibitor of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (KD = 1.2 nM). Inhibits smoothened agonist effects with an IC50 of 20 nM (in Shh-LIGHT2 cells). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 373.5 |
| 分子式 | C23H27N5 |
| 可溶性/溶解性 | Soluble to 25 mM in ethanol and to 50 mM in DMSO |
| CAS号 | 304909-07-7 |
| 参考文献 | Chenet al (2002) Small molecule modulation of smoothened activity. Proc.Natl.Acad.Sci.USA. 991407. |
