| 货号 | 1325/50 |
| 别名 | 5-Methyl-3-[3-[3-[4-[2-(2,2,2,-trif |
| 供应商 | Tocris |
| 生物活性 | Subtype-selectiveα1A-adrenoceptor antagonist (pKi = 9.6 for human cloned α1A receptors). Displays 126- and 50-fold selectivity over human α1Bandα1D receptors respectively. Active in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 462.89 |
| 分子式 | C20H25F3N4O3.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 232953-52-5 |
| 参考文献 | Conleyet al (2001) The role of α1-adrenoceptors and 5-HT1A receptors in the control of the micturition reflex in male anaesthetized rats. Br.J.Pharmacol. 133 61. PMID: 11325795. Williamset al (1999) In vitro α1-adrenoceptor pharmacology of Ro 70-0004 and RS-100329, novel α1A-adrenoceptor selective antagonists. Br.J.Pharmacol. 127 252. PMID: 10369480. Shannon Kavaet al (1998) α1L-Adrenoceptor mediation of smooth muscle contraction in rabbit bladder neck: a model for lower urinary tract tissues of man. Br.J.Pharmacol. 123 1359. PMID: 9579731. |