| 货号 | 5583/50 |
| 别名 | 4-Butoxy-N-[1,4-dihydro-2-(4-methox |
| 供应商 | Tocris |
| 生物活性 | Potent and selective FPR2 agonist (EC50 = 40 nM). Induces Ca2+ mobilization in FPR2 but not FPR1-transfected mast cells. Induces neutrophil chemotaxis and degranulation in vitro. Reduces neutrophil and lymphocyte counts in bronchoalveolar lavage fluid in a mouse lung injury model. Anti-inflammatory. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 445.51 |
| 分子式 | C26H27N3O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Corminboeufet al (2014) FPR2/ALXR agonists and the resolution of inflammation. J.Med.Chem. 58 537. PMID: 25365541. Zhouet al (2007) Pharmacological characterization of a novel nonpeptide antagonist for formyl peptide receptor-like 1. Mol.Pharmacol. 72 976. PMID: 17652444. |