PF 04885614 (50 MG)
货号：
4916/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 4916/50 |
| 别名 | 1-Methyl-[1-[4-(4-trifluoromethoxy)phenyl]-imidazol-2-yl]-ethanamine |
性能| 供应商 | Tocris |
| 生物活性 | Potent NaV1.8 inhibitor (IC50 = 53 nM for human NaV1.8 channel). Exhibits selectivity for hNaV1.8 over hNaV1.6, hNaV1.7, hNaV1.1, hNaV1.2 and hNaV1.5 (IC50 values are 4.2, 7.0, 11, 16 and 27 μM respectively). Orally bioavailable. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 285.26 |
| 分子式 | C13H14F3N3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Bagalet al (2013) Discovery of selective NaV1.8 modulators for the treatment of chronic pain. Abstract. 4th RSC/SCI Symp. on Ion Channels as Ther. Targ. |
