NSC 319726 (50 MG)
货号：
5065/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 5065/50 |
| 别名 | 1-Azetidinecarbothioic acid [1-(2-pyridinyl)ethylidene]hydrazide |
性能| 供应商 | Tocris |
| 生物活性 | Reactivator of mutant p53. Restores wild type p53 structure and function to the p53R175 mutant. Inhibits growth of fibroblasts expressing the p53R175 mutation (IC50 = 8 nM). Also inhibits growth of xenograft tumors expressing the p53R175mutationin vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 234.32 |
| 分子式 | C11H14N4S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol with gentle warming |
| 参考文献 | Yuet al (2012) Allele-specific p53 mutant reactivation. Cancer Cell 21 614. PMID: 22624712. |
