货号 | 1866/50 |
别名 | 1,4-Dihydro-2,6-dimethyl-4-(3-nitro |
供应商 | Tocris |
生物活性 | Potent blocker of store-operated Ca2+ channels; inhibits capacitative Ca2+ influx in HL-60 cells (IC50 = 1.7 mM). |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 398.41 |
分子式 | C21H22N2O6 |
可溶性/溶解性 | Soluble to 10 mM in ethanol with gentle warming and to 10 mM in DMSO |
CAS号 | 544478-19-5 |
参考文献 | Szikraet al (2009) Calcium homeostasis and cone signaling are regulated by interactions between calcium stores and plasma membrane ion channels. PLoS ONE 4 e6723. PMID: 19696927. Szikraet al (2008) Depletion of calcium stores regulates calcium influx and signal transmission in rod photoreceptors. J.Physiol. 586 4859. PMID: 18755743. Harperet al (2003) Dihydropyridines as inhibitors of capacitative calcium entry in leukemic HL-60 cells. Biochem.Pharmacol. 65 329. PMID: 12527326. |