| 货号 | 1584/50 |
| 别名 | N-(4-Acetylphenyl)-2-[4-(2,3,6,7-te |
| 供应商 | Tocris |
| 生物活性 | Potent and selective adenosine A2B receptor inverse agonist (Ki values are 1.39, 157, 112 and 230 nM for human A2B, A1, A2A and A3 receptors respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >96 % |
| 计算分子量 | 503.56 |
| 分子式 | C27H29N5O5 |
| 可溶性/溶解性 | Soluble to 5 mM in DMSO |
| CAS号 | 264622-53-9 |
| 参考文献 | Liet al (2007) ZM241385, DPCPX, MRS1706 are inverse agonists with different relative intrinsic efficacies on constitutively active mutants of the human adenosine A2B receptor. J.Pharmacol.Exp.Ther. 320 637. PMID: 17077318. Kiec-Kononowiczet al (2001) New developments in A1 and A2 adenosine receptor antagonists. Pure Appl.Chem. 731411. Kimet al (2000) Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A2B adenosine receptors. J.Med.Chem. 43 1165. PMID: 10737749. |