MIM1 (50 MG)
货号：
4762/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 4762/50 |
| 别名 | 4-(E)-[[(2Z)-2-cyclohexylimino)-4-methyl-1,3-thiazol-3(2H)-yl]imino]methyl]benzene-1,2,3-triol |
性能| 供应商 | Tocris |
| 生物活性 | Inhibitor of Mcl-1; selectively targets the BH3-binding pocket. Induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells. Also blocks Mcl-1-mediated suppression of tBID-induced Bax activation in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 计算分子量 | 347.43 |
| 分子式 | C17H21N3O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Cohenet al (2012) A competitive stapled peptide screen identifies a selective small molecule that overcomes MCL-1-dependent leukemia cell survival. Chem.Biol. 19 1175. PMID: 22999885. |
