| 货号 | 4141/50 |
| 别名 | [2-[(4-Fluorophenyl)amino]-4-methyl |
| 供应商 | Tocris |
| 生物活性 | Allosteric potentiator of α7,α4β2 and α4β4 nAChRs; displays selectivity against α3β4 nAChRs. Thought to potentiate agonist-evoked α7 responses by binding within the nAChR transmembrane region. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 318.39 |
| 分子式 | C15H11FN2OS2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| 参考文献 | Younget al (2008) Potentiation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site. Proc.Natl.Acad.Sci. 10514686. Broadet al (2006) Identification and pharmacological profile of a new class of selective nicotinic acetylcholine receptor potentiators. J.Pharmacol.Exp.Ther. 318 1108. PMID: 16738207. |