JNJ 303 (50 MG)
货号：
3899/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 3899/50 |
| 别名 | 2-(4-Chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide |
性能| 供应商 | Tocris |
| 生物活性 | Potent IKs blocker (IC50 = 64 nM). Displays no effects on other cardiac channels; IC50 values are 3.3, >10, 11.1 and 12.6 μM for INa, ICa, Ito and IKr currents respectively. Prolongs QT and causes unprovoked torsades de pointes (TdP). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 440.98 |
| 分子式 | C21H29ClN2O4S |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO |
| CAS号 | 878489-28-2 |
| 参考文献 | Towartet al (2009) Blockade of the IKs potassium channel: an overlooked cardiovascular liability in drug safety screening? J.Pharm.Toxicol.Meth 601. |
