IT1t dihydrochloride (50 MG)
货号：
4596/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 4596/50 |
| 别名 | N,N'-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester dihydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Potent CXCR4 antagonist (IC50 = 1.1 nM in calcium mobilization assays). Orally available. Blocks interaction with the HIV envelope protein, gp120 (IC50 = 7 nM, inhibition of X4-tropic HIV-1IIIB attachment). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 479.57 |
| 分子式 | C21H34N4S2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Thomaet al (2008) Orally bioavailable isothioureas block function of the chemokine receptor CXCR4 in vitroandin vivo. J.Med.Chem. 51 7915. PMID: 19053768. |
