IQ 1 (50 MG)
货号：
4713/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 4713/50 |
| 别名 | 2-[2-(4-Acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)acetamide |
性能| 供应商 | Tocris |
| 生物活性 | Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells; enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation. Upregulates expression of Oct4andSox2 transcription factors. Binds to serine/threonine phosphatase PP2A and prevents PP2A/Nkd interaction. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 362.42 |
| 分子式 | C21H22N4O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Miyabayashiet al (2007) Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency. Proc.Natl.Acad.Sci.U S A 104 5668. PMID: 17372190. |
