IOX 1 (50 MG)
货号：
4464/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 4464/50 |
| 别名 | 8-Hydroxy-5-quinolinecarboxylic acid; 5-carboxy-8HQ |
性能| 供应商 | Tocris |
| 生物活性 | Histone demethylase JMJD inhibitor (IC50 values are 0.12, 0.17, 0.2, 0.3, 0.6 and 1 μM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively). Cell permeable; inhibits JMJD2A-mediated H3K9me3 demethylation in HeLa cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 189.17 |
| 分子式 | C10H7NO3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in 1eq. NaOH |
| 参考文献 | Kinget al (2010) Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors. PLoS One. 5 e15535. PMID: 21124847. |
