| 货号 | 1749/50 |
| 别名 | α-Amino-4-hexyl-2,3-dihydro-3-oxo-5- |
| 供应商 | Tocris |
| 生物活性 | Group I mGlu receptor antagonist (Ki values are 140 and 110 μM at mGlu1a and mGlu5a receptors respectively). Decreases sEPSCs in rat pyramidal neurons in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 256.3 |
| 分子式 | C12H20N2O4 |
| 可溶性/溶解性 | Soluble to 20 mM in 1eq. NaOH |
| CAS号 | 334887-43-3 |
| 参考文献 | Bandrowskiet al (2003) Baseline glutamate levels affect group I and II mGluRs in layer V pyramidal neurons of rat sensorimotor cortex. J.Neurophysiol. 89 1308. PMID: 12626613. Madsenet al (2001) Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors. J.Med.Chem. 44 1051. PMID: 11297452. |