DQP 1105 (50 MG)
货号：
4491/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 4491/50 |
| 别名 | 5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-γ-oxo-1H-pyrazole-1-butanoic acid |
性能| 供应商 | Tocris |
| 生物活性 | Noncompetitive NMDA receptor antagonist; displays over 50-fold selectivity for GluN2D- and GluN2C-containing receptors over GluN2B-, GluK2-, GluA1- and GluN2A-containing receptors (IC50 values are 2.7, 8.5, 121, 153, 198 and 206 μM, respectively). Reduces frequency of channel opening. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >97 % |
| 计算分子量 | 558.42 |
| 分子式 | C29H24BrN3O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Ackeret al (2011) Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators. Mol.Pharmacol. 80 782. PMID: 21807990. |
