货号 | 2241/50 |
别名 | 4-[(5,6-Dihydro[2,3'-bipyridin]-3(4H |
供应商 | Tocris |
生物活性 | Partial agonist at α7-containing neuronal nicotinic receptors and antagonist at α4β2 and other nicotinic receptors. Displays specific cognition-enhancing effects; improves long-term memory in rats. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 364.32 |
分子式 | C19H21N3.2HCl |
可溶性/溶解性 | Soluble to 100 mM in water and to 25 mM in DMSO |
CAS号 | 32013-69-7 |
参考文献 | Stevenset al (1998) Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology 136 320. PMID: 9600576. Kemet al (1997) Anabaseine is a potent agonist on muscle and neuronal alpha-bungarotoxin-sensitive nicotinic receptors. J.Pharmacol.Exp.Ther. 283 979. PMID: 9399967. Arendashet al (1995) Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21. Brain Res. 674 252. PMID: 7796104. |