CMPDA (50 MG)
货号:
4373/50 基本售价:
10549.0 元 规格:
50 mg
产品信息
概述货号 | 4373/50 |
别名 | N,N'-(1,4-Phenylenedi-2,1-ethanediyl)bis-2-propanesulfonamide |
性能供应商 | Tocris |
生物活性 | Positive allosteric modulator of GluR2 receptors (EC50 values are 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assay). Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 376.53 |
分子式 | C16H28N2O4 |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
参考文献 | Timmet al (2011) Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Mol.Pharmacol. 80 267. PMID: 21543522. |