Cinnabarinic acid (50 MG)
货号：
4119/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 4119/50 |
| 别名 | 2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid |
性能| 供应商 | Tocris |
| 生物活性 | mGlu4 receptor agonist. Activates mGlu4 receptors in transiently transfected HEK293 cells; selective over all other mGlu subtypes (mGlu1, mGlu2 and mGlu5-8). Decreases cAMP levels in native cultured cerebellar granule cells. Also counteracts excitotoxic neuronal cell death induced by NMDA in mixed cultures of cortical cells; displays neuroprotective activity. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 300.22 |
| 分子式 | C14H8N2O6 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Fazio (2012) Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type-4 metabotropic glutamate receptors. Mol.Pharmacol. Feb 6 Epub ahead of print. PMID: 22311707. |
