| 货号 | 3505/50 |
| 别名 | 4-[[(2,3-Dihydro-1,1,3,3-tetramethy |
| 供应商 | Tocris |
| 生物活性 | RARα-selective agonist (Ki = 2 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 351.4 |
| 分子式 | C21H21NO4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Dilworthet al (1999) Ligand-dependent activation of transcription in vitro by retinoid acid receptor α/retinoid X receptor α heterodimers that mimics transactivation by retinoids in vivo. Proc.Natl.Acad.Sci.USA 961995. Gehinet al (1999) Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. Chem.Biol. 6 519. PMID: 10421757. Tanejaet al (1996) Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RARβ2andHoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts. Proc.Natl.Acad.Sci.USA 936197. |