| 货号 | 4177/50 |
| 别名 | 2-[[2-(4-Bromophenyl)-6-methyl-4-py |
| 供应商 | Tocris |
| 生物活性 | GPR119 receptor agonist (EC50 = 2.5 μM in HEK293 cells expressing human GPR119). Enhances insulin secretion stimulated by glucose in vivo. Stimulates proglucagon gene promoter actvity. Orally available. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 308.17 |
| 分子式 | C13H14BrN3O |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Chepurnyet al (2013) Stimulation of Proglucagon Gene Expression by Human GPR119 in Enteroendocrine L-cell Line GLUTag. Mol.Endocrinol. 27 1267. PMID: 23798572. Yoshidaet al (2010) Identification of a novel GPR119 agonist, AS1269574, with in vitroandin vivo glucose-stimulated insulin secretion. Biochem.Biophys.Res.Commun. 400 437. PMID: 20804735. |