| 货号 | 0671/50 |
| 别名 | 6-Isopropoxy-9-xanthone-2-carboxyli |
| 供应商 | Tocris |
| 生物活性 | Antagonist at prostaglandin EP1(pA2 = 6.8) and EP2(Ki = 350 nM) receptors. Also weakly inhibits DP receptors (pA2 = 4.45). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 298.3 |
| 分子式 | C17H14O5 |
| 可溶性/溶解性 | Soluble to 100 mM in 1.1eq. NaOH and to 100 mM in DMSO |
| CAS号 | 33458-93-4 |
| 参考文献 | van der Merweet al (2009) Prostaglandin E2 derived from cyclooxygenases 1 and 2 mediates intestinal epithelial ion transport stimulated by the activation of protease-activated receptor 2. J.Pharmacol.Exp.Ther. 329 747. PMID: 19190238. Kiriyamaet al (1997) Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br.J.Pharmacol. 122 217. PMID: 9313928. Keery and Lumley (1988) AH 6809, a prostaglandin DP-receptor blocking drug on human platelets. Br.J.Pharmacol. 94 745. PMID: 2460179. Colemanet al (1985) AH6809, a prostanoid EP1-receptor blocking drug. Br.J.Pharmacol. 85273P. |