A 844606 (50 MG)
货号：
4477/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 4477/50 |
| 别名 | 2-(Hexahydro-5-methylpyrrolo[3,4-c]pyrrol-2(1H)-yl)-9H-xanthen-9-one |
性能| 供应商 | Tocris |
| 生物活性 | Selectiveα7 nicotinic acetylcholine receptor (nAChR) partial agonist (EC50 values are 1.4 and 2.2 μM at human and rat receptors respectively). Displays no measurable effect on α4β2 nAChRs. Stimulates α7 nAChR-induced ERK1/2 phosphorylation in PC12 cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 320.38 |
| 分子式 | C20H20N2O2 |
| 可溶性/溶解性 | Soluble to 5 mM in ethanol with gentle warming |
| 参考文献 | Briggset al (2008) Alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues. Br.J.Pharmacol. 153 1054. PMID: 18157163. |
