| 货号 | 2753/50 |
| 别名 | 3-[2-[(4-Chlorophenyl)thiophenyl]-N |
| 供应商 | Tocris |
| 生物活性 | Activator of soluble guanylyl cyclase (sGC). Activates basal sGC and synergistically activates sGC in the presence of NO. Relaxes cavernosum smooth muscle in vitro and induces penile erections in rats. Induces a sustained increase in skin blood flow in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 425.41 |
| 分子式 | C21H25ClN2OS.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 538368-27-3 |
| 参考文献 | Kotzkiet al (2013) Anodal iontophoresis of a soluble guanylate cyclase stimulator induces a sustained increase in skin blood flow in rats. J.Pharmacol.Exp.Ther. 346 424. PMID: 23838678. Evgenovet al (2006) NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential. Nat.Rev.Drug Discov. 5 755. PMID: 16955067. Milleret al (2003) A-350619: a novel activator of soluble guanylyl cyclase. Life Sci. 72 1015. PMID: 12495780. |