4mu8C (50 MG)
货号：
4479/50 基本售价：
10549.0 元 规格：
50 mg
产品信息
概述| 货号 | 4479/50 |
| 别名 | 7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde |
性能| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of IRE1α ribonuclease (RNase) activity (IC50 = 60 nM). Blocks substrate access to the active site of IRE1α. Inactivates IRE1α-mediated mRNA degradation. Displays no effect on the IRE1α-related endoribonuclease RNase L. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 204.18 |
| 分子式 | C11H8O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Crosset al (2012) The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule. Proc.Natl.Acad.Sci.USA 109 E869. PMID: 22315414. |
