| 货号 | 4083/50 |
| 别名 | 5-Ethyl-7,8-dimethoxy-1H-pyrrolo[3, |
| 供应商 | Tocris |
| 生物活性 | Potent and selective GSK-3β inhibitor (IC50 values are 34 and 304 nM in the presence of 10 and 100 μM ATP respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 286.28 |
| 分子式 | C15H14N2O4 |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO |
| 参考文献 | Zouet al (2010) Benzo[e]isoindole-1,3-diones as potential inhibitors of glycogen synthase kinase-3 (GSK-3). Synthesis, kinase inhibitory activity, zebrafish phenotype, and modeling of binding mode. J.Med.Chem. 53 994. PMID: 20030405. Zhonget al (2009) Characterization and development of novel small-molecules inhibiting GSK3 and activating wnt signaling. Mol.Biosyst. 5 1356. PMID: 19823752. |