17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
货号：
9000347-1mg 基本售价：
10528.0 元 规格：
1 mg
产品信息
概述| 货号 | 9000347-1mg |
| 描述 | Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-keto-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity.1,2 It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 µM).2 |
| 别名 | EFOX;17-oxo-DPA;17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Jie, M.S.F.L.K., and Pasha, M.K. Fatty acids, fatty acid analogues and their derivatives. Natural Product Reports 607-629 (1998).
2.Groeger, A.L.,Cipollina, C.,Cole, M.P., et al. Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids. Nature Chemical Biology (2010).
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| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥95% |
| 计算分子量 | 344.5 |
| 分子式 | C22H32O3 |
| CAS号 | 1233715-33-7 |
| 稳定性 | ≥ 6 months |
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