| 货号 | 2518/50 |
| 别名 | 2-(3-Pyridinyl)-1-azabicyclo[3.2.2] |
| 供应商 | Tocris |
| 生物活性 | Selective nicotinic α7 receptor agonist (EC50 = 440 nM). Also displays weak partial agonist/antagonist activity at β-subunit-containing receptors. Neuroprotective. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 275.22 |
| 分子式 | C13H18N2.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 700834-58-8 |
| 参考文献 | Papkeet al (2005) Rhesus monkey α7 nicotinic acetylcholine receptors: comparisons to human α7 receptors expressed in Xenopus oocytes. Eur.J.Pharmacol. 524 11. PMID: 16266703. Marreroet al (2004) The neuroprotective effect of 2-(3-Pyridyl)-1-azabicyclo[3.2.2]nonane (TC-1698), a novel α7 ligand, is prevented through angiotensin II activation of a tyrosine phosphatase. J.Pharmacol.Exp.Ther. 309 16. PMID: 14722323. |