| 货号 | 3642/50 |
| 别名 | 6,7-Dimethoxy-N-(4-phenoxyphenyl)-4 |
| 供应商 | Tocris |
| 生物活性 | Potent, competitive dual site (ATP- and peptide-binding) Src kinase inhibitor (IC50 values are 44 and 88 nM for Src and Lck respectively). Inhibits VEGFR2 and c-fms at higher concentrations (IC50 values are 0.32 and 30 μM respectively). Can be used in parallel with PP 1 (Cat. No. 1397) and PP 2 (Cat. No. 1407) to inhibit Src family kinases. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 373.4 |
| 分子式 | C22H19N3O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 179248-59-0 |
| 参考文献 | Bainet al (2007) The selectivity of protein kinase inhibitors: a further update. Biochem.J. 408 297. PMID: 17850214. Tianet al (2001) Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines. Biochem. 407084. |