| 货号 | 3284/50 |
| 别名 | 1-(4-Amino-6,7-dimethoxy-2-quinazol |
| 供应商 | Tocris |
| 生物活性 | Selectiveα1B-adrenoceptor antagonist (Ki values are 0.3, 1.9 and 2.6 nM at human α1B,α1Aandα1D receptors respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 568.49 |
| 分子式 | C26H33N5O5.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 173059-17-1 |
| 参考文献 | Morstonet al (2007) α1A-adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries. Br.J.Pharmacol. 150 112. PMID: 17115072. Bremneret al (2000) Ligand design for α1 adrenoceptor subtype selective antagonist. Bioorg.Med.Chem. 8 201. PMID: 10968279. Testaet al (1997) Pharmacological characterization of the uroselective alpha-1 antagonist Rec 15/2739 (SB 216469): Role of the alpha-1L adrenoceptor in tissue selectivity, part II. J.Pharmacol.Exp.Ther. 281 1284. PMID: 9190864. |