Pyr3 (50 MG)
货号：
3751/50 基本售价：
10489.5 元 规格：
50 mg
产品信息
概述| 货号 | 3751/50 |
| 别名 | 1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid |
性能| 供应商 | Tocris |
| 生物活性 | Selective antagonist of the canonical transient receptor potential channel 3 (TRPC3). Inhibits TRPC3-mediated Ca2+ influx (IC50 = 0.7 μM) and suppresses activation of nuclear factor of activated T cells (NFAT). Inhibits hypertrophic responses in cardiomyocytes. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 456.63 |
| 分子式 | C16H11Cl3F3N3O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 1160514-60-2 |
| 参考文献 | Kiyonakaet al (2009) Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound. Proc.Natl.Acad.Sci. 1065400. |
