| 货号 | 2957/50 |
| 别名 | 5-Chloro-3-ethyl-N-[2-[4-(1-piperid |
| 供应商 | Tocris |
| 生物活性 | Potent CB1 receptor allosteric modulator (pEC50 = 8.24). Significantly increases binding of the CB1 agonist [3H]CP 55.940 (pKb = 5.67) and decreases binding of the CB1 inverse agonist [3H]SR 141716A (pKb = 5.95). Inhibits CB1 receptor antagonist efficacy in vitro(pKb = 7.57). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 409.95 |
| 分子式 | C24H28ClNO3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 868273-06-7 |
| 参考文献 | Ross (2007) Allosterism and the cannabinoid CB1 receptors: the shape of things to come. Trends Pharmacol.Sci. 28 567. PMID: 18029031. Priceet al (2005) Allosteric modulation of the Cannabinoid CB1 receptor. Mol.Pharmacol. 68 1484. PMID: 16113085. |