| 货号 | 3960/50 |
| 别名 | N-[2-(Benzoylamino)-6-benzothiazoly |
| 供应商 | Tocris |
| 生物活性 | Potent, selective and reversible ceramide kinase (CerK) inhibitor (IC50 = 12 nM in vitro). Displays selectivity for CerK over sphingosine kinases (IC50≥100μM) and other lipid kinases. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 431.55 |
| 分子式 | C25H25N3O2S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 5 mM in ethanol |
| CAS号 | 362003-83-6 |
| 参考文献 | Grafet al (2009) A secondary assay for ceramide kinase inhibitors based on cell growth inhibition by short-chain ceramides. Anal.Biochem. 384 166. PMID: 18831956. Grafet al (2009) Targeting ceramide metabolism with a potent and specific ceramide kinase inhibitor. Mol.Pharmacol. 74925. Niwaet al (2009) Ceramide kinase deficiency impairs microendothelial cell angiogenesis in vitro. Microvasc.Res. 77 389. PMID: 19323974. |