| 货号 | 1054/50 |
| 别名 | 3-[3-(Dimethylamino)propyl]-4-hydro |
| 供应商 | Tocris |
| 生物活性 | A selective competitive 5-HT1B(5-HT1Dβ) silent antagonist with pKB values of 7.3 and 6.3 for human cloned 5-HT1B and 5-HT1D receptors respectively and only weak binding at a number of other 5-HT subtypes. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 448.39 |
| 分子式 | C23H25N3O2.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 172854-55-6 |
| 参考文献 | MacLeanet al (1996) Evidence for 5-HT1-like receptor-mediated vasoconstriction in human pulmonary artery. Br.J.Pharmacol. 119 277. PMID: 8886409. Connoret al (1995) Use of GR55562, a selective 5-HT1D antagonist, to investigate 5-HT1D receptor subtypes mediating cerebral vasoconstriction. Cephalalgia 15 (suppl. 14) 99. Walshet al (1995) The activity of 5-HT1D receptor ligands at cloned human 5-HT1Dα and 5-HT1Dβ receptors. Eur.J.Pharmacol. 287 79. PMID: 8666030. |