货号 | 2025/50 |
别名 | 4-[[3-[(1E)-2-(4-Cyclobutyl-2-thiaz |
供应商 | Tocris |
生物活性 | Potent, selective CysLT1(LTD4) leukotriene receptor antagonist (IC50 = 6.4 nM). Inhibits LTD4-induced bronchoconstriction in guinea pigs when administered intravenously, orally or by aerosol. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 412.55 |
分子式 | C23H28N2O3S |
可溶性/溶解性 | Soluble to 10 mM in ethanol and to 100 mM in DMSO |
CAS号 | 128312-51-6 |
参考文献 | O'Donnell (1991) Ro 24-5913: a potent, specific, orally active LTD4 antagonist. Ann.N.Y.Acad.Sci. 629 413. PMID: 1659286. O'Donnellet al (1991) Pharmacologic actions of Ro 24-5913, a novel antagonist of leukotriene D4. J.Pharmacol.Exp.Ther. 259 751. PMID: 1658310. |