| 货号 | 1409/50 |
| 别名 | (E)-(±)-2-Amino-4-methyl-5-phosphono |
| 供应商 | Tocris |
| 生物活性 | Potent, selective and competitive NMDA antagonist (Ki = 310 nM for inhibition of [3H]-CPP binding in rat brain). Centrally active upon oral administration in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 237.19 |
| 分子式 | C8H16NO5P |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 127910-32-1 |
| 参考文献 | D'Hoogeet al (1999) Effects of competitive NMDA receptor antagonists on excitatory amino-acid-evoked currents in mouse spinal cord. Fundam.Clin.Pharmacol. 13 67. PMID: 10027090. Loscher and Honack (1991) Anticonvulsant and behavioural effects of two novel competitive N-methyl-D-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamazepine. J.Pharmacol.Exp.Ther. 256 432. PMID: 1671593. Fagget al (1990) CGP 37849 and CGP 39551: novel and potent competitive N-methyl-D-asparate receptor antagonists with oral activity. Br.J.Pharmacol. 99 791. PMID: 1972895. |