货号 | 1304/50 |
别名 | N-[3-[3-(-Fluorophenoxy)phenyl]-1-m |
供应商 | Tocris |
生物活性 | Potent, selective inhibitor of 5-lipoxygenase. Long half-life and high oral bioavailability in vivo. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 316.33 |
分子式 | C17H17FN2O3 |
可溶性/溶解性 | Soluble to 3 mM in ethanol and to 3 mM in DMSO |
CAS号 | 134470-38-5 |
参考文献 | Yeadonet al (1993) Effect of BW B70C, a novel inhibitor of arachidonic acid 5-lipoxygenase, on allergen-induced bronchoconstriction and late-phase lung eosinophil accumulation in sensitised guinea-pigs. Agents Actions 38 8. PMID: 8480540. Payneet al (1991) Hydroxamic acids and hydroxyureas as novel, selective 5-lipoxygenase inhibitors for possible use in asthma. Agents Actions Suppl. 34 189. PMID: 1793063. Salmonet al (1990) Inhibition of 5-lipoxygenase: development of hydroxamic acids and hydroxyureas as potential therapeutic agents. Adv.Prost.Throm.Leuk.Res. 21 109. PMID: 1847758. |