| 货号 | 2937/50 |
| 别名 | 5-(2-Ethyl-2,3-dihydro-1H-indene-2- |
| 供应商 | Tocris |
| 生物活性 | Selectiveα2-adrenergic receptor antagonist (Ki values are 1.1, 1.0, 0.89, 1300 and 6500 nM for α2A,α2B,α2C,α1Aandα1B receptors respectively). Brain penetrant. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 248.75 |
| 分子式 | C14H16N2.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| CAS号 | 104075-48-1 |
| 参考文献 | Jurgenset al (2007) α2A adrenergic receptor activation inhibits epileptiform activity in the rat hippocampal CA3 region. Mol.Pharmacol. 71 1572. PMID: 17341653. Puurunenet al (2001) An α2-adrenergic antagonist, atipamezole, facilitates behavioral recovery after focal cerebral ischemia in rats. Neuropharmacology 40 597. PMID: 11249969. Virtanenet al (1989) Highly selective and specific antagonism of central and peripheral alpha 2-adrenoceptors by atipamezole. Arch.Int.Pharmacodyn.Ther. 297 190. PMID: 2567152. |