Tie2 Inhibitor 7
货号:
19535-5mg 基本售价:
10402.0 元 规格:
5 mg
产品信息
概述货号 | 19535-5mg |
描述 | Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 µM.1. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 µM.1 This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization.1 |
性能供应商 | Cayman |
应用文献 |
1.Liu, J.,Lin, T.H.,Cole, A.G., et al. Identification and characterization of small-molecule inhibitors of Tie2 kinase. FEBS Letters 582(5), 785-791 (2008).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 529.6 |
分子式 | C31H35N3O5 |
CAS号 | 1020412-97-8 |
稳定性 | ≥ 2 years |
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