INH1 (50 MG)
货号：
3551/50 基本售价：
10192.1 元 规格：
50 mg
产品信息
概述| 货号 | 3551/50 |
| 别名 | N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]benzamide hydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Hec1 inhibitor. Binds Hec1, inhibiting its association with Nek2 and kinetochores. Causes arrest of mitosis and inhibits proliferation in breast cancer cell lines (GI50= 10 - 20 μM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 344.86 |
| 分子式 | C18H16N2OS.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| CAS号 | 313553-47-8 |
| 参考文献 | Wuet al (2008) Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. Cancer Res. 68 8393. PMID: 18922912. |
