| 货号 | 4628/50 |
| 别名 | 2-(3,4-Dimethoxyphenyl)-4H-naphtho[ |
| 供应商 | Tocris |
| 生物活性 | Selective aryl hydrocarbon receptor (AHR) modulator (SAhRM). Suppresses expression of CD55 and CD46 induced by IL-1β in an inflammatory tumor cell microenvironment; exhibits no effect on basal CD55 or CD46 expression. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 332.35 |
| 分子式 | C21H16O4 |
| 可溶性/溶解性 | Soluble to 5 mM in DMSO |
| 参考文献 | Labrecqueet al (2012) Distinct roles for aryl hydrocarbon receptor nuclear translocator and Ah receptor in estrogen-mediated signaling in human cancer cell lines. PLoS ONE 7 e29545. PMID: 22235307. Narayananet al (2012) Selective aryl hydrocarbon receptor modulator-mediated repression of CD55 expression induced by cytokine exposure. J.Pharmacol.Exp.Ther. 342 345. PMID: 22553215. Murrayet al (2011) Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3',4'-dimethoxy-α-naphthoflavone. Mol.Pharmacol. 79 508. PMID: 21127131. |