BRD 4354 ( )
货号：
6010/50 基本售价：
9954.1 元 规格：
50 mg
产品信息
概述| 货号 | 6010/50 |
| 别名 | 5-Chloro-7-[(4-ethyl-1-piperazinyl)-3-pyridinylmethyl]-8-quinolinol |
性能| 供应商 | Tocris |
| 生物活性 | HDAC5 and HDAC9 inhibitor (IC50 values are 0.85 and 1.88 μM, respectively). Also weakly inhibits HDAC4, HDAC6, HDAC7 and HDAC8 (IC50 values are 3.88 - 13.8 μM). Exhibits >20-fold selectivity for HDAC5/9 over HDAC1/2/3. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 382.89 |
| 分子式 | C21H23ClN4O |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO and to 50 mM in ethanol |
| 参考文献 | Boskovicet al (2016) Inhibition of zinc-dependent histone deacetylases with a chemically triggered electrophile. ACS Chem.Biol. 11 1844. PMID: 27064299. |
