货号 | 0332/10 |
别名 | (2S,1'S,2'R)-2-(Carboxycyclopropyl)gl |
供应商 | Tocris |
生物活性 | Potent and competitive inhibitor of both glial and neuronal uptake of glutamate, aspartate and cysteate. |
运输条件 | Blue Ice |
存放说明 | Ambient |
计算分子量 | 159.14 |
分子式 | C6H9NO4 |
可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH |
CAS号 | 117857-95-1 |
参考文献 | Yamashitaet al (1995) Inhibition by folded isomers of L-2-(carboxycyclopropyl)glycine of glutamate uptake via the human glutamate transporter hGluT-I. Eur.J.Pharmacol. 289 387. PMID: 7621914. Nakamuraet al (1993) (2S,3S,4R)-2-(Carboxycyclopropyl)glycine, a potent and competitive inhibitor of both glial and neuronal uptake of glutamate. Neuropharmacology 32 833. PMID: 7901789. Kawaiet al (1992) 2-Carboxycyclopropyl)glycine: binding, neurotoxicity and induction of intracellular free Ca2+ increase. Eur.J.Pharmacol. 211 195. PMID: 1319341. Shinozakiet al (1989) Potent NMDA-like actions and potentiation of glutamate responses by conformational variants of a glutamate analogue in the rat spinal cord. Br.J.Pharmacol. 98 1213. PMID: 2692753. |