| 货号 | 1036/50 |
| 别名 | 4-(2-[7-Amino-2-(2-furyl)[1,2,4]tri |
| 供应商 | Tocris |
| 生物活性 | Potent and highly selective A2A adenosine antagonist, with a pA2 of 9.02 for A2A receptors in guinea pig cardiac vasculature and selectivities of 1000, 91 and 500,000 over A1, A2B and A3 sites respectively. Active in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 337.34 |
| 分子式 | C16H15N7O2 |
| 可溶性/溶解性 | Soluble to 5 mM in ethanol and to 100 mM in DMSO |
| CAS号 | 139180-30-6 |
| 参考文献 | Keddieet al(1996)In vivo characterisation of ZM 241385, a selective adenosine A2A receptor antagonist. Eur.J.Pharmacol. 301 107. PMID: 8773453. Poucheret al (1996) Pharmacodynamics of ZM 241385, a potent A2a adenosine receptor antagonist, after enteric administration in rat, cat and dog. J.Pharm.Pharmacol. 48 601. PMID: 8832494. Poucheret al (1995) The in vitro pharmacology of ZM 241385, a potent, non-xanthine, A2a selective adenosine receptor antagonist. Br.J.Pharmacol. 115 1096. PMID: 7582508. |