| 货号 | 1996/50 |
| 别名 | 4-Methyl-5-(1-methylethoxy)-9H-pyri |
| 供应商 | Tocris |
| 生物活性 | Potent, selective and competitive benzodiazepine receptor antagonist (IC50 values are 0.4 and 0.7 nM for inhibition of [3H]-flunitrazepam binding to rat cerebellum and hippocampus respectively). Similar in vivo profile to flumazenil (Ro 15-1788, Cat No. 1328); produces anxiogenic effects in some behavioral tests and anxiolytic effects in others. Orally active. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 348.82 |
| 分子式 | C18H20N2O3.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 50 mM in DMSO |
| CAS号 | 89592-45-0 |
| 参考文献 | Cordaet al (1987) Enhancement of γ-aminobutyric acid binding by the anxiolytic β-carbolines ZK 93423 and ZK 91296. J.Neurochem. 48 1355. PMID: 2881979. File and Baldwin (1987) Effects of β-carbolines in animal models of anxiety. Brain Res.Bull. 19 293. PMID: 3315125. Jensenet al (1984) Evaluation of the β-carboline ZK 93 426 as a benzodiazepine receptor antagonist. Psychopharmacology 83 249. PMID: 6089247. |