货号 | 3951/50 |
别名 | N1,N4-Di-2-pyridinyl-1,4-benzenedim |
供应商 | Tocris |
生物活性 | Potent chemokine receptor type 4 (CXCR4) antagonist (EC50 = 0.3 nM). Inhibits CXCR4/stromal cell-derived factor-1 (SDF-1)-mediated modulation of cAMP in vitro(EC50 = 1.2 nM). |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >99 % |
计算分子量 | 290.36 |
分子式 | C18H18N4 |
可溶性/溶解性 | Soluble to 25 mM in DMSO |
CAS号 | 55778-02-4 |
参考文献 | Zhanet al (2007) Discovery of small molecule CXCR4 antagonists. J.Med.Chem. 50 5655. PMID: 17958344. Reyeset al (2002) Pyridinium N-(2'-azinyl)aminides: regioselective synthesis of N-(2-pyridyl) substituted polyamines. Chem.Inform. 34. |