货号 | 0498/50 |
别名 | cis-(±)-3,4-Dichloro-N-methyl-N-[2-( |
供应商 | Tocris |
生物活性 | κ-opioid agonist and anticonvulsant. Perhaps acts as an NMDA antagonist. |
运输条件 | Blue Ice |
存放说明 | Ambient |
计算分子量 | 391.77 |
分子式 | C18H24Cl2N2O.HCl |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 112465-94-8 |
参考文献 | Sethy and Sage (1992) Modulation of release of acetylcholine from the striatum by a proposed excitatory amino acid antagonist U-54494A: comparison with known antagonists, diazepam and phenytoin. Neuropharmacology 31 111. PMID: 1348110. Proiettiet al(1991)In vitro depressant effects of U-54494A, an anticonvulsant related to kappa opioids in the hippocampus. Neuropharmacology 30 637. PMID: 1656303. Voigtlanderet al (1987) U-54494A: a unique anticonvulsant related to kappa opioid agonists. J.Pharmacol.Exp.Ther. 243 542. PMID: 2824750. |